Institute of Clinical and Preventive Medicine


September 25th, 2018  

Two articles by KPMI authors published in the latest issue of Helicobacter magazine  

The latest issue of the HELICOBACTER magazine is bublished. In this issue of the magazine with a high index of citation (above 4) are published even two articles authors of which are KPMI's new researchers, residents - Olga Sjomina and Sabine Skrebinska.

Congratulations to the authors with these publications!

In addition to the  above mentioned full-scale publications, the journal also published numerous reports from the Latvia's stand reports of from the European Helicobacter and Microbiota Study Group XXXIst International Workshop, most of the co-authors are from KPMI.

The latest issue of the magazine online available: HERE.

September 19th, 2018  

In Munich reports on progress in the H2020 project SNIFFPHONE

KPMI researchers at the SIEMENS office in Munich International H2020 Project SNIFFPHONE consortium gave a report to the European Commission's project supervisory specialists and their associated industry experts on the progress achieved over the project over a 3 year period. Although the main task of the SNIFFPHONE project is the development of modern technology, especially positive feedback from specialists was received directly from clinical studies. KPMI specialists was responsible for the whole clinical part of the project and all work was done in Latvia.

On behalf of KPMI, thanks to leading researcher Inese Poļaka, researcher Edgars Vasiļjevs, as well as a participating student and volunteer team for the good work done.

In turn, due to the involvement of the participants in the study, thanks to the chief executives at the Latvian Oncology Center of the Riga Eastern Clinical University Hospital - Aija Kārkliņa and in Rezekne -  Aiga Rūdule. Thanks also for the staff of  Digestive Disease Center GASTRO.

September 17th, 2018 

EHMSG XXXI International Congress is attended by 33 representatives from Latvia

At the European Helicobacter and Microbiota Study Group XXXIst International Workshop, which took place in Lithuania, Kaunas, from 13 to 15 September, Latvia was the third of the countries with the largest number of participants.

Among the participants from Latvia there was a group of researchers from KPMI, which delivered 11 stand's reports and 1 oral report.

The results of the GISTAR pilot study in Kazakhstan and other researches carried out by the institute were reported in the form of stand reports.

Residents and graduates of the University of Latvia (Zane Dzērve, Linda Mežmale, Anna Krīgere, Danute Ražuka-Ebela, Ieva Lašhina, Petra Kriķe, Edgars Vasiļjevs) participated with the stand's reports. In turn, KPMI Director and Leading researcher, professor Mārcis Leja, performed with an oral report.

We are proud to mention that KPMI Leading researcher, professor Sergejs Isajevs received the award for the best stand report.

Congress theme - "Helicobacter & Microbiota in Inflammation & Cancer".

                          More pictures:  Picture_1, Picture_2Picture_3, Picture_4,
                          Picture_5Picture_6Picture_7, Picture_8Picture_9, Picture_10,
September 11th, 2018  

Researchers of KPMI are among the authors of a paper published in an International Journal of Medical Oncology 

On September 6th in a monthly peer-reviewed open-access medical journal covering oncology "Cancer Medicine" is published an article entitled "Evidence for PTGER4,PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level". 

Among the authors there are two researchers of the KPMI - leading researcher M. Leja and researcher E. Gasenko.

The article is available in the open access section of Wiley Online Library - one of the largest and most authoritative collections of online magazines, books and research resources covering life, health, social and physical sciences.

The summary of the article is available at HERE.

September 10th, 2018  

Researchers Group from KPMI will attend EHMSG XXXIst International Workshop

European Helicobacter and Microbiota Study Group - EHMSG XXXIst International Workshop on Helicobacter & Microbiota in Inflammation & Cancer will take place in Kaunas, Lithuania,  September 13 - 15.

Researchers Group from KPMI will take part in the congress with reports and posters.

In September last year, the director of the Institute of Clinical and Preventive Medicine of the University of Latvia, Professor of the Faculty of Medicine, gastroenterologist Mārcis Leja, were elected as the President of the EHMSG.

September 7th, 2018 

Leading researchers of the institute participate in The Europe Biobank Week 2018

On September 4 - 7 in Antwerp (Belgium) leading researchers of the institute Signe Mežinska and Ģirts Šķenders, participated in the Europe Biobank Week organized by the European Research Infrastructure Consortium, the BBMRI-ERIC (Biobanking and BioMoucular Resources Research Infrastructure - European Research Infrastructure Consortium). The European BioBank Week is one of the most significant annual biobanks congresses that discuss current and future challenges for bio-banking, as well as new opportunities for co-operation. 

More information on Biobank week available HERE.

                          More pictures: Picture_2
September 3rd, 2018 

Starting the new academic year, the leaders of the institutes are welcomed 

At the general meeting of employees of the University of Latvia, which took place on August 31st  in the Great Hall, Professor Indriķis Muižnieks, the Rector of the University of Latvia, congratulated the newly elected academic staff, the new deans and the heads of the institutes. Greetings and gratitudes were given.

Marcis Leja, Director of KPMI, received a gratitude on excellence in science.

July 5th, 2018  

Baltic and Eurasia Masterclass in Clinical Oncology will take place on 12-15 of July  

The European School of Oncology is very glad to invite you to attend the “BALTIC AND EURASIA MASTERCLASS IN CLINICAL ONCOLOGY ” that will be held in Riga, Latvia on 12-15 July 2018.

Chair: N. Pavlidis (GR), F. Peccatori (IT), Host Chair: J. Eglitis (LV).

Representatives of KPMI also participate in organization of the masterclass. 

A more detailed description of the application can be found here.

Further details can be found on the flyer that can be downloaded here or on the website.

June 28th, 2018  

Discusses the possibilities of support to oncological research in Latvia

On June 27th, at the Academic Centre of University of Latvia, staff members of the KPMI - director, professor M. Leja, deputy director G. Šķenders and leading researcher D.Šantare met with representatives of Ltd. Mikrotīkls - co-owner John Tully and donation / support program representative Inga Narkeviča. During the meeting the possibilities of support to oncological research in Latvia were discussed. M. Leja presented representatives of Ltd. Mikrotīkls with data of the Institute's activities on the directions of oncology and oncology prevention. Guests were introduced to the Institute's scientific work: the internationally recognized gastric cancer prevention study GISTAR (, which also includes several satellite investigations of pre-cancerous conditions diagnosis, Helicobacter pylori, its eradication capabilities and gut microbiome. Existing applications to detect volatile organic compounds and the use of oncological diseases diagnostics were also demonstrated. After the presentation representatives of Ltd. Mikrotīkls were shown laboratories and biobank premises where research is being carried out.

In conclusion, the director of Infrastructure Department of the University of Latvia Marģers Počs introduced the existing research premises of the Academic Centre of University of Latvia and demonstrated the development plan of the camps of the University of Latvia.

For reference - Ltd. Mikrotīkls is trying to support oncological researches in Latvia, and is looking for research institutes in Latvia that are active in this field.

                             In the picture (from the left):
                            Director of KPMI M.Leja, director of Infrastructure Department
                            of the University of Latvia Marģers Počs​  and co-owner 
                            of Ltd. Mikrotīkls  John Tully  
                            More pictures: Picture_1, Picture_2
June 25th, 2018 

A record number of abstracts from Latvia has been submitted for EHMSG 2018 annual conference  

Meeting of the Organizing Committee for the European Helicobacter and Microbiota Study group (EKMSG) annual conference is taking place in Vienna. A record number of abstracts from Latvia has been submitted for the conference this year: Latvia is rating number 4 among all the countries globally with 16 abstracts submitted. Most of the abstracts are originating from our institute. The conference will take place in Kaunas, Lithuania September 13-15, 2018.

More information available

June 22nd, 2018 


Midsummer night, and bonfires on the hill

Burn for the man who makes way for the Light:

He must increase and I diminish still,

Until his sun illuminates my night.


June 21th, 2018 

A collaborative project for piloting GISTAR in Ukraine submitted for the UK GLOBAL HEALTH Initiative funding  

Under the coordination of Dr. Mangesh Thorat (Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Barts & The London School of Medicine and Dentistry Queen Mary University of London) a project application “Ukraine pilot of GISTAR trial- H. pylori eradication, pepsinogen testing and FIT for prevention of gastric and colorectal cancer mortality (GISTAR-U)”  was submitted.

The Ukrainian partners include Vinnytsia National Pirogov Memorial University (PI: Prof. Vyacheslav Chernobrovyj), Dnepropetrovsk National University (PI: Prof. Maryna Shcherbynina) and National Cancer Centre, Ukraine (PI: Prof. Andrii Lukashenko).

June 20th, 2018 

KPMI research achievements are being demonstrated to representative of the European Commission

European Commission’s director-general for research and innovation Jean-Eric Paquet was visiting Latvia. On June 20th, a meeting was held at the University of Latvia, in which University of Latvia leading research groups demonstrated their work and achievements in field of research. During the meeting, director of KPMI M. Leja informed about institute's main sudies in oncology, including about the progress of the GISTAR study.

                            In the picture (from the left):
                           Rector of the University of Latvia prof. I.Muižnieks,
                           prof. A.Ambainis and European Commission
                           director- general for research and innovation
                           J.E.Paquet during a visit at the University of Latvia     
June 18th, 2018 

Begins the IV World Congress of Latvian Scientists  

Today, the IV World Congress of Latvian Scientists begins at the Latvian National Library. Congress will take place from 18 to 20 of June.
The Congress is one of the most ambitious events of the Centenary of the Republic of Latvia, organized by Ministry of Education and Science, and bringing together scientists of Latvian origin from all over the world, as well as their strategic partners and supporters, in order to jointly look at the accomplishments and define the future tasks of Latvian science for the development of the state and society.
The Congress is organized by the Ministry of Education and Science in co-operation with the Association of Latvian Universities, scientific institutions and diaspora organizations.
Representatives of KPMI, including prof. Maris Leja and others are participating in the congress.

More information about the Congress HERE.

June 15th, 2018  

At Uppsala Health Summit discuss on improving care of oncologic patients   

Leading researcher of KPMI Signe Mežinska on June 14-15 participates in the Uppsala Health Summit, which theme this year is treatment of oncological diseases. At the conference there are discussed changes in priorities and health policies that are needed to improve the availability of diagnostics and healthcare for cancer patients. S.Mežinska participates in the working group on the role of biobanks in the improvement of global oncological patient care. More than 200 experts from 33 countries representing healthcare, politics, science, industry and civil society have been invited to the Uppsala Health Summit.

More information about the Summit HERE.

June 12th, 2018 

Scandinavian Journal of Gastroenterology publishes an article by the Research Group of KPMI

On June 11th publishing house Taylor & Francis at Scandinavian Journal of Gastroenterology published an article made by the Research group of KPMI about comparison of various tests for the detection of helicobacteria of stomach. The first author of the article is Sabine Skrebinska, a physician-resident. Voluminous work materials has been summarized, in which endoscopic stomach examinations were performed at the Digestive Diseases Centre GASTRO, but morphological investigations - in the Academic Histology Laboratory. Research data suggest that it is inadequate to use serological examinations (blood tests) as the only test for helicobacteria testing in daily practice.

A summary of the article HERE.

June 11th, 2018 

In Vienna prepares for the United European Gastroenterology Week

In Vienna, the European Gastroenterology House hosted the last meeting of the Scientific Committee in preparation for the 2018 European major event in the specialty - the United European Gastroenterology Week (UEG Week). Director of the KPMI M.Leja also participated in the work of the Scientific Committee.

More information on UEG Week available HERE.

                             In the picture:
                            Members of the Scientific Committee of the Congress     
June 8th, 2018 

Scientific assistant of KPMI D.Pupola defends master's thesis

On June 7th,  at the Academic Centre of University of Latvia KPMI Scientific assistant Dārta Pūpola defended her Master Thesis on the "Long-term Effects of Amoxicillin and Clarithromycin Combined Therapy on Gastrointestinal Microbioma". The supervisor of the master's thesis is Mārcis Leja ( Director of the LU KPMI), but scientific adviser - Dita Gudrā (LV BMC). The result is a Master's degree in Biology.

                            2018. gada kongresa Zinātniskās komitejas locekļi     
June 7th, 2018 

The director of the Institute of Clinical and Preventive Medicine reports at the meeting in Washington

June 3rd, 2018. A meeting of the regular working group of the International Healthy Stomach Initiative took place in Washington, DC. It was decided to mark the International Stomach Health Day on the 2nd of October each year. The date was chosen in light of the daylight release of the Nobel Prize winners B.Marshal's and R.Varren's Helicobacter Revelation, which has transformed the fate of millions of people around the world. At the meeting the report on gastric cancer prevention activities in Europe was delivered by the director of the Institute of Clinical and Preventive Medicine of the University of Latvia, professor Mārcis Leja.

June 5th, 2018. At the Digestive Diseases Week, tooking place in Washington, DC, professor M. Leja presented a report on the most valuable findings in the field of microbiome research in Europe. The congress is attended by 14,000 professionals from all around the world. The report was given at the session "Best of European Gastroenterology Week" .

June 6th, 2018. At the US National Cancer Institute M. Leja gave an hour-long report about the ongoing researches on gastric cancer in Latvia. After the meeting, several gatherings were held, including with the Co-ordinating Specialists on Global Activities for possible further expansion of cooperation.

                             In the picture:
                            M. Leja with participants of the meeting at the
                            National Cancer Institute     
June 5th, 2018  

In Cambridge discuss technology and data analytics solutions for medical development

In Cambridge, UK, Microsoft together with its partners, hosted an international workshop on IT and analytical solutions: Intelligent Medicines: Future Decoded, which was attended by KPMI leading researcher Inese Poļaka. This seminar was attended by IT, medical and pharmaceutical industry and science representatives to discuss future medicine: treatment personalization, data analysis and safety, and patient involvement. The latest technologies and good practices in various research and companies were presented: patient status monitoring, detailed data acquisition and analysis, adaptation of diagnostics and observation of patients' lifestyle, use of new technologies (genetic, etc., analyzes in science and diagnostics), etc. During this event, new knowledge and contacts were gained, which will allow further development of KPMI research activities and competencies.

May 25th, 2018 

A review seminar on the four years of the VPP 2014-2017 BIOMEDICINE IV project is underway

Today, at the University of Latvia's Academic Center for Natural Sciences is taking place a review seminar on the four years of the Implementation of the VPP 2014 - 2017 BIOMEDICINE - the IV Project "Gastrointestinal Mortality Reduction Opportunities under Latvian Conditions". Professors Mārcis Leja and Valdis Pīrāgs are opening the seminar. The participants are introduced to the project's goal, structure and main tasks. The main project performers present the audience with the activities carried out within the framework of the project. The total performance indicators for the 4 years completed within the framework of the IV project will be summarized by July 31st this year.

                             In the picture:
                            Participants of the seminar during the discussion     
May 18th, 2018 

Latvian Cancer screening experts participate in the Eurasian Cancer Screening Conference in Minsk

Latvian cancer screening specialists, along with leading experts from European countries, the United States and Canada, participated in the Eurasian Cancer Screening Conference, which took place in Minsk from 17 to 18 of May. The conference was organized by colleagues from the Belarusian Oncology Center in cooperation with experts from the United States National Cancer Institute's Global Health Center to develop cancer screening in countries where so far they have not succeeded with successful solutions, namely, in the former Soviet countries. Latvia was represented at the event by director of KPMI Mārcis Leja (colorectal and stomach cancer), specialist of Riga East University Hospital Māra Epermane (breast cancer screening), and Juris Plonis from the P.Stradin Clinical University Hospital (prostate cancer). As a result of the meeting, the cooperation and plans launched in the framework of the CanCon project (EU Joint Action Against Cancer) will continue. CanCon project completed last year.

More information about the Conference HERE.

                             In the picture:
                            Participants of the seminar during the discussion     
May 8th, 2018 

Discuss Ethics and responsible Research and Innovation (RRI) Aspects in Collaborative Research Projects

Yesterday on May 7th, a seminar on ethical and responsible research and innovation (RRI) aspects of co-operation projects was organized by the Institute of Clinical and Preventive Medicine of the University of Latvia. The seminar was attended by the Institute's collaborators from the University of Tampere (Finland) - researchers Veiko Ikonen and Janika Tyynela. Within the framework of the seminar, the current issues of ethics, data security and responsibility of scientists were discussed, as well as an implementation of the General Data Protection Regulation in research practice.

                             In the picture:
                            Participants of the seminar during the discussion     
May 7th, 2018 

KPMI Priority Research Areas in year 2018

1) GISTAR study on the prevention of malignancy in digestive diseases (, incl. its expansion (regional pilot studies) outside of Latvia

2) Development of BioBank

3) Microbiological studies (digestive system, upper respiratory tract)

4) Studies on volatile markers (exhaled markers: gastric cancer and control group, population group, tuberculosis and control group; skin markers: tuberculosis and control group)

5) Studies on tuberculosis and lung diseases

6) Development of new research areas, incl. in cooperation with strategic partners (eg HIV infection, hepatitis C)



April 12th, 2018 

At the International Conference also reports data from H.pylori strains obtained in Latvia

The initial results on the H.pylori global genome project have been reported during the VIII International symposium on Helicobacter pylori and gastric cancer in Belo Horizonte, Brazil. Data from H.pylori strains being obtained during the studies in Latvia were included.

                          In the picture:
                         Constanza Camargo with the poster     

  • Doctoral Studies School invites to a seminar on the human gut microbiome

April 11th, 2018. In May at RIGA EAST UNIVERSITY HOSPITAL  "Gaiļezers" educational sector will be host the next Doctoral School workshop devoted to the Human Gut Microbioma. The seminar will be led by a microbiologist researcher Darta Pupola. Details of the exact time and location of the seminar will be provided.

In the picture: microbiologist Darta Pupola

  • We invite to participate in the IV World Congress of Latvian Scientists  June 18 - 20

April 9th, 2018. Celebrating the centenary of the Latvian state, from 18 to 20 June 2018, the Latvian National Library will host an important event in the science of Latvia - the IV World Congress of Latvian Scientists. The Congress is one of the most ambitious events of Latvia's 100th anniversary organized by the Ministry of Education and Science, which will bring together scholars of Latvian origin from all over the world, as well as their strategic partners and supporters, in order to jointly look at the accomplishments and define the future tasks of Latvian science for the development of the state and society.

More information about the congress, its course and program, current events, speakers, registration for participation and submission of the stand's reports can be viewed here.

  • Baltic and Eurasia Masterclass in Clinical Oncology, 12-15 July 2018 -  Riga, Latvia April 6th, 2018

April 6th, 2018. The European School of Oncology is very glad to invite you to attend the “BALTIC AND EURASIA MASTERCLASS IN CLINICAL ONCOLOGY ” that will be held in Riga, Latvia on 12-15 July 2018.

Chair: N. Pavlidis (GR), F. Peccatori (IT), Host Chair: J. Eglitis (LV).

A more detailed description of the application can be found here.

Further details can be found on the flyer that can be downloaded here or on the website.


  • Institute is inviting  to the seminar, headed by asoc. prof. Lilian Tzivian

April 5th, 2018. Researchers interested in the successful publication process are kindly invited to the seminar on April 16th, 16:00 - 17:30, RAKUS, Gailezers, Hipokrāta Street 2 - cabinet No. 223.

A lecture is planned on how to quickly and correctly write a manuscript, find the appropriate magazine to publish it and make it easier the process of publication . Together we will focus on how  to correctly plan a manuscript, which parts are needed and how much it needs to be, which tables and images are needed, and how to respond to reviewers.
The lecture will combine knowledge from three courses on this subject: Course "Good practices in scholarly publishing" (lecturer Dr. Katarzina Gaca, Western European consultant from the Elsevier magazine group), course "Scientific writing" (lecturer Jane Schroder, Editor of the journal Environmental and Health perspectives ) and course "The deep secrets of getting your paper published" (lecturer Mark Nieuwenhuijsen, ISGlobal Director, editor of Occupational and Environmental Medicine magazine).

Content of the lecture - research protocol, its coordination with foreign partners, coordination with local co-authors, publishing opportunities, fast writing of articles.

In the picture: Lilian Tzivian

  • The team of the institute wishes Happy Easter!

March 29th, 2018.

  • Institute of Clinical and Preventive Medicine also presented at the The European Consortium myCROBIOME  

March 5th, 2018. In the European House of Gastroenterology in Vienna, meeting of the newly established consortium myCROBIOME was held. More than 20 organizations from Europe, Israel, and the US are represented. The consortium forming initiative was supported by a grant from the United European gastroenterology (UEG).

  • The University of Latvia signs a memorandum of cooperation with Kazakhstan's Innovative Medical Technology Organization  

February 21th, 2018. Vice-rector of the University of Latvia Valdis Seglins and Chairman of the Innovative Medical Technology Organization (Kazakhstan) Niyaz Malayev signed a memorandum of cooperation between the two organizations.
The document is based on the promotion of scientific cooperation not only in the medical and educational sector, but also in clinical medicine and public health, with the main emphasis on wider use of innovative technologies in diagnostic and therapeutic areas. The purpose of the Memorandum is to promote closer co-operation between organizations and in communication with governmental and non-governmental institutions.
It is expected that this memorandum will be the basis for developing further cooperation, looking for the possibility of joint project and research realization in the future.


  • The University of Latvia will host the International Gastric Cancer Prevention Research Forum for a week  

February 8th, 2018. The International Gastric Cancer Prevention Research Forum, organized by the Institute of Clinical and Preventive Medicine of the University of Latvia, will take place on February 19-23. It will bring together leading European experts and representatives from countries with high levels of gastric cancer, as well as representatives from international professional and patient organizations. During the week, various topical issues related to research on gastric cancer prevention will be discussed, the projects implemented in Latvia will be presented and opportunities for future cooperation with foreign partners will be discussed.

More information about the Forum is available here.

  • The team of the Institute is wishing wonderful Holidays and a Happy New Year!

December 29th, 2017.

  • The University of Latvia is presented by IKPM at Horizon 2020 Health Partnering Event

December 7th, 2017. Horizon 2020 Health Partnering Event is taking place in Brussels. Institute of Clinical and Preventive medicine is representing University of Latvia in this event. Bilateral meetings with representatives from several leading European Universities and Research Organizations is scheduled.

More information on this event here.

In the picture: : Philippe CUPERS (Acting Head of Unit, Strategy, Health Directorate, DG RTD,. European Commission) introducing the H2020 2018-2020 program.

  • Professor M.Leja plans the scientific program of European Gastroenterology Week

December 4th, 2017. November 30 – December 1, 2017 the director of the Institute of Clinical and Preventive Medicine of the University of Latvia M.Leja was participating in the work of the Scientific Committee of UEG (United European gastroenterology) for planning the scientific program of European Gastroenterology Week, 2018.

In the picture: Participants of the Scientific Committee of UEG

  • Student of the world-famous American pathologist visits Latvia

October 31st, 2017. On October 24-25th  Prof. Maria Blanca Piazuelo, professor of the University of Vanderbilt, visited Latvia.
On October 24th M.B. Piazuelo met with the leading researchers of the Institute of Clinical and Preventive Medicine of the University of Latvia -  Sergey Isaev, Arnis Kirchner and Sergey Parchutin. During the meeting M.B. Piazuelo was introduced to the GISTAR Information System and Histology Slide Storage System. There were discussed several topics – entering of the histological findings of the stomach biopsy in the GISTAR system, and the adaptation of histology slide resolution for system and research purposes. The definition of pre-cancerous stomach conditions, the methods used and their interpretation were discussed by scientists. During the meeting, samples of the biopsy of the most complicated patients in the GISTAR study were also analyzed.
On October 25th M.B. Piazuelo met with the scientific director of the GISTAR study, Professor of the University of Latvia, Marcis Leja. During the meeting GISTAR research activities and the progress on publications were discussed.
For information - Maria Blanca Piazuelo is one of the world's leading specialists in detecting pre-cancerous stomach conditions. This is the second time Prof. Piazuelo, within the framework of the collaborative study, arrives in Riga. It should be noted that prof. Piazuelo is a student and work successor of Pelayo Correa, the world-famous American pathologist.

In the pictures: Prof. Maria Blanca Piazuelo  /  Prof. Maria Blanca Piazuelo and Dr. med Sergey Isajev